New Cleveland Clinic research finds up to 5% of Americans carry genetic mutations associated with cancer risk
New Cleveland Clinic research reveals that up to 5% of Americans – approximately 17 million people – carry genetic mutations or “variants” linked to increased cancer susceptibility, regardless of risk…
Genetic testing reduces risks from chemotherapy for gastrointestinal cancer patients
For some patients with gastrointestinal (GI) cancers like colorectal and pancreatic cancer, chemotherapy can cause severe, sometimes life-threatening side effects in those who carry certain genetic variants that can impact…
NIH researchers develop AI agent that improves accuracy of gene set analysis by leveraging expert-curated databases
Researchers at the National Institutes of Health (NIH) have developed an artificial intelligence (AI) agent powered by a large language model (LLM) that creates more accurate and informative descriptions of…
Brain changes in Huntington’s disease decades before diagnosis will guide future prevention trials
Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington’s disease, finds a…
All stem cell therapies are not created equal
Researchers from University of California San Diego have found that two of the most frequently administered stem cell therapies, which are often used interchangeably, actually contain completely different types of…
Scientists map networks regulating gene function in the human brain
A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders. These maps detail…
Immune Cells Identified as Key Players in Brain Health
Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues…